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apalutamide will lower the level or impact of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP2C19 inducer, with drugs which are CYP2C19 substrates may end up in decrease exposure to these drugs.Adjunct use, if apprehension, stress and anxiety or acute strai